Naturlose offers natural suger taste without calorie to diabetics

healthys-smileNaturlose (Tagatose) a natural sugar supplement product launched by Spherix, promises to help the diabetics to enjoy sweet dishes even better now with almost no side effects.

What is the speciality of Naturlose?

The major attribute of Naturlose is its taste. Naturlose (Tagatose) occurs in nature and has an excellent, sucrose-like taste, with no cooling effect or aftertaste. Standard taste-test panels on Naturlose showed it to be 92% as sweet as sucrose.

What is the status (clinical) of Naturlose?

Human clinical trials conducted at the Department of Endocrinology, University of Maryland School of Medicine on both type 2 diabetics and normal subjects receiving a daily regimen of Naturlose (tagatose) for 12 months showed that both groups gradually and consistently lost weight at medically desirable rates.

In what way Naturlose will benefit Diabetics?

naturlose_logo_smallNaturlose (tagatose) has been proven to be useful in treating Type 2 diabetes. Tests on genetically diabetic rats relieved all symptoms. Human clinical trials on Type 2 diabetic patients and normal controls were run at the Department of Endocrinology, University of Maryland School of Medicine. Tagatose produced no change in fasting glucose or insulin levels. In addition, pre-treatment with tagatose attenuated the rise in serum glucose after oral glucose or sucrose intake.

These findings prompted further research, which concluded, “d-Tagatose may be a useful therapeutic adjunct in the management of type 2 diabetes mellitus.” A small clinical trial was then conducted as a follow-up. After a 2-month run-in period, patients with type 2 diabetes were given 15-g doses of tagatose in each of three daily meals for 1 year. The study confirmed and extended the usefulness of tagatose in treating the disease. Spherix’s U.S. Patents 5,215,591 and 5,356,879 protect the use of tagatose to treat diabetes.

How effective Naturlose is against Hyperglycemia?

Hyperglycemia is generally recognized as the major cause of aging. The glucose-induced linking of protein molecules in muscle and the brain causes these organs to atrophy. In an early investigation of the influence of Naturlose (tagatose) on blood glucose levels, experiments were conducted on normal and genetically diabetic rats. Tagatose was shown not to increase glucose levels, and, in addition, the sugar was found to be anti-hyperglycemic.

diabetes0401Even more surprisingly, these studies found that tagatose relieved the symptoms of diabetes in the diseased animals ( Diabetes ). Tagatose taken prior to glucose or sucrose ingestion blunts the rise in blood glucose. In addition, glucose is required for the metabolism of the tagatose absorbed into the bloodstream, thereby reducing the body’s store of glucose and inhibiting hyperglycemia. Spherix’s U.S. Patents 5,447,917 and 5,356,879 cover this property.

Is there any side effects of Naturlose?

Naturlose’s anti-plaque, non-carcinogenic, and anti-halitosis properties advocate its use in oral and other products, and make it a potential agent for the prevention of dental caries, gingivitis and other periodontal diseases, halitosis, and for tooth whitening.

The Department of Health and Human Services’ Healthy People 2010 Objectives “recognizes dental caries as the single most common chronic disease of childhood, and states that 30 percent of adults have untreated dental decay.” Naturlose (tagatose) has been demonstrated to be noncariogenic in two studies using human volunteers.

On December 2, 2002, the FDA authorized an amendment to a health claim (21 CFR 101.80) on sugar alcohols and dental caries to include tagatose. The FDA has allowed the claim that tagatose does not cause tooth decay, and that use of tagatose may actually reduce the risk of that disease. The FDA statement said, “Based on the totality of publicly available scientific evidence, we have now determined that the sugar D-tagatose . is not fermented by oral bacteria to an extent sufficient to cause the erosion of dental enamel.

Therefore,” the Agency stated, “we have concluded that D-tagatose does not promote dental caries.”

What are the additional advantages of Naturlose?

Anti- Biofilm

The U.S. Public Health Service’s Communicable Disease Center states that up to 65% of bacterial infections in humans are biofilms in nature. Biofilms are conglomerations of microorganisms that consist of one or more species of bacteria, fungi, algae, and protozoa, singly or as a mixture, in which the participants adhere together in an aqueous environment to form a film attached to surfaces such as teeth, gums, human and animal blood vessels, medical implant materials, soil particles, metals, and plastics. The total annual cost of the adverse consequences of biofilms runs into the billions of dollars.

snf11cake_682_578044aNaturlose (tagatose) has been demonstrated to have the potential for preventing plaque development, for disassembling existing plaque, and for combating the adverse health, physical and environmental effects of biofilms (Cisar et al. “Specificity of coaggregation reactions between human oral streptococci and strains of Actinomyces viscosus or Actinomyces naeslundii“, Infect. Immun., 24:742-752. 1979). The possibility for administering Naturlose in the treatment of biofilms include its use: in, or as, a food; in, or as, a drug; and as an ingredient in toothpaste and mouthwash.

Fights Colon Cancer

Naturlose (tagatose) has been shown to act as a prebiotic , aiding digestion; to produce elevated amounts of butyrates that have been reported to fight colon cancer; to combat intestinal pathogens, including E.coli, while promoting the growth of favorable microorganisms, such as lactic acid bacteria (Bertelsen H, Jensen BB, Buemann B, D-tagatose-a novel low-calorie bulk sweetener with prebiotic properties, World Rev Nutr Diet 1999;85:98-109).


Naturlose (tagatose) has prebiotic properties that improve digestion (Bertelsen H, Jensen BB, Buemann B, D-tagatose-a novel low-calorie bulk sweetener with prebiotic properties, World Rev Nutr Diet 1999;85:98-109). Long appreciated in Europe and Asia, prebiotic properties are of growing interest in the United States. Tagatose selects for more favorable or benign microbial flora in the intestine and against potentially pathogenic organisms such as Escherichia coli. Moreover, tests have shown that ingestion of tagatose produces larger amounts of desirable short-chain fatty acids, in particular butyrate, than are produced by a normal diet. The many beneficial effects of butyrate include defense against colon cancer .

Increase in Beneficial HDL Cholesterol

A low baseline HDL-cholesterol in our population is seen commonly in obese patients with type 2 diabetes and has been shown to be a major risk factor for coronary heart disease. Daily ingestion of Naturlose (tagatose) with food leads to weight loss and significant increases in HDL-cholesterol in patients with type 2 diabetes. In a human clinical trial conducted at the Department of Endocrinology, University of Maryland School of Medicine, four male and four female subjects with type 2 diabetes were studied for 14 months. A 2-month run-in period was followed by a 12-month treatment period during which time 15g of oral tagatose was taken three times a day with food. A progressive and marked rise in HDL-cholesterol was observed following dietary supplementation with tagatose throughout the 12-month intervention period in all 8 subjects.

Thus it is evident from the above discussion that it Naturlose can be a revolutionary product in supplementing sucrose and beneficial to a very large extent, which would help the taste buds of the diabetics to taste sweet. Moreover with the additional benefits that Naturlose promises, no doubt it will bring out the sweet smiles on the face of the diabetics.

Filed under Blood Sugar Testing, Diabetes, Diabetes awareenss, Diabetic Diet, Featured Article, Insulin, Liver, NIDDM, Obesity | Tags: , , , , , , , , | Comment Below


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