Link between diabetes and cancer: obesity and depression

A new study finds diabetic cancer patients are more at risk to die from cancer. Thus the study is thought to have solved the unknown relation between the two- cancer and diabetes.

Both diabetes and cancer act as two major reasons of death world wide and especially in the USA. Though many studies took place, none of them have been able to define relation between the two. Researchers have cited various probable reasons like role of high blood sugar for tumor growth. Another study suggests that cancer patients often neglect their diabetes. However, a team of researchers in Baltimore, Maryland seem to have defined the relation.

In a meta analysis, the team of the researchers led by Frederick Brancati, looked at nearly 23 well-designed studies that looked at cancer patients who had diabetes at the time of diagnosis. They identified various probable risk factors. For the first place, there is obesity. Many people with type 2 diabetes are also obese, and obesity is linked to a greater risk of some types of cancer.

In insulin resistance the body’s cells are unable to respond adequately to the blood-sugar regulating hormone insulin resulting in an increased buildup of insulin and glucose in the blood stream. Insulin resistance is often a precursor to type 2 diabetes, and one of the causes of obesity, heart disease, stroke and other conditions. Insulin is known to stimulate cell proliferation, so an overproduction or high concentration of the hormone may be partially responsible for cancer development. Insulin resistance has been associated with cancers of the colon and rectum, breast, and pancreas.

Then comes the risks of depression. Researchers also find about 10 to 40 percent of people with diabetes also experience depression, and they can have more severe episodes than those who don’t have diabetes.

University of Missouri based researcher Richard Hellman, M.D. said,

“If you have cancer and you have diabetes, you have to be more vigilant. Make sure that your care is well coordinated so that your diabetes care remains excellent, any of your cardiovascular evaluations are up-to-date, and the doctors are talking to each other.”


Filed under Diabetes, Diabetic Cancer, NIDDM, Obesity | Tags: , , , , | Comment Below


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