Indian scientists have succeeded in inducing the most prevalent type 2 diabetes in a freshwater fish, which could turn out to be a convenient animal model to treat the disease.
The disease was induced by feeding the Indian perch (Anabas testudineus) with a compound called palmitate. This compound belongs to a class called free fatty acid, which is among the major reasons for development of diabetes.
Scientists also found development of insulin resistance. Insulin resistance is a condition in which insulin, a chemical produced by the pancreas, is not able to act on glucose leading to accumulation of glucose in the blood.
“Nutritionally induced insulin-resistant perch could be a good model to study type 2 diabetes mellitus,” scientists from the Indian Institute of Chemical Biology, Kolkata and School of Life Sciences, Visva-Bharati, Santiniketan, reported in Current Science.