According to an article published in a journal (Psychiatric Services) of the American Psychiatric Association, in the year 2004, the study among 1692 patients, shows about the increased risk in males patients who were exposed to Seroquel for at least 60 days, compared with the exposure of a newer class of antipsychotics including clozapine and Seroquel with an older class of drugs.
A 2006 study in the Journal of Clinical Psychiatry noted that more than 40 percent of 920 patients with diabetes who were exposed to antipsychotics for three months had received the class of drugs that includes Seroquel.
Another study from the U.S. Food & Drug Administration in 2004 found that reports of high glucose levels increased with the number of Seroquel prescriptions between 1997 and 2002,
However, as per AstraZeneca spokesman Tony Jewell, these are very minute selection of scientific data available on Seroquel, but analyzing the total evidence it is found that Seroquel is safe and effective.
U.K’s second largest drug maker, AstraZeneca, faces about 9,000 lawsuits in the U.S. over claims Seroquel causes diabetes and other health problems.