Recent study by the Boston researchers have found that gene test may not be fruitful in diabetes treatment. It is no better than asking some general traditional questions regarding weight, family history or smoking status.
The study, published in the New England Journal of Medicine, presents analysis of more than 16 genes linked to type 2 diabetes. It found that the information they provided was no better than traditional risk factors, including blood sugar levels.
The team of the researchers, led by Dr. James Meigs looked at 18 sites on the human genome and followed 2,377 people taking part in a larger medical study for 28 years. Genes pointed to diabetes in just 4 percent of the volunteers.
In the second stage of the study they have examined 16 genetic sites on more than 18,800 Swedish and Finnish volunteers. At the end, they have concluded that gene tests plays a very small effect on the ability to predict the future development of type 2 diabetes.
The lead researcher said,
“The results suggest that ‘personalized medicine’ that is made possible by the expanded understanding of genetics is not yet as useful for the prediction of the risk of diabetes in adults as it is for other potential applications.”
Source: Reuters
Filed under Diabetes, NIDDM | Tags: blood sugar levels, Boston researchers, diabetes treatment, genetic sites, human genome, New England Journal of Medicine, type 2 diabetes | Comment Below
Related?
Gene Can Protect You Form Diabetes and Heart Disease April 26th, 2006 Genes can play a major defensive role against both type 2 diabetes and heart disease, a new study finds. Individuals with the trait aren't immune from the conditions, researchers say, but a study of nearly 7 900 subjects found that they are as much as 48 percent less likely to suffer from either illness.
Monogenic Diabetes, the Biggest Cause Of Diabetes In Children & Young AdultsMay 16th, 2008 Monogenic Diabetes are caused when one or more mutation occurs in a single gene. This type of mutations are very rare but has a great impact and lead to diabetes, at early stage.
New gene responsible for diabetes and obesity foundOctober 21st, 2008 A new research done by the researchers of Germany has revealed that, natural mutation in the Tbc1d1 gene protects the body of mice against diabetes and obesity. During the research the researchers identified a new kind of gene which not only keeps the mice lean but also protects it against diabetes despite a high-fat diet.
Molecular Link Between High Fat Consumption and Type 2 Diabetes Discovered; Hope for Type 2 PreventionJanuary 3rd, 2006 According to scientists at the University of California, San Diego (UCSD) School of Medicine, a single gene encoding the enzyme GnT-4a glycosyltransferase (GnT-4a) is key to enabling the beta cells in the pancreas to sense blood glucose levels and appropriately produce insulin. However, this enzyme is suppressed by a high-fat diet, resulting in pancreatic beta cell failure and eventually leading to type 2 diabetes.
Researchers find link between sleeping disorder and diabetesDecember 8th, 2008 Northwestern University researchers have found link between flaws in the sleeping habit and diabetes. The variant in the gene M1NR1B, boosts the likelihood of elevated blood sugar and Type 2 diabetes.
Clinical Trial Raises Hope for Type 2 (NIDDM) Diabetes Cure for non-Obese With SurgeryApril 24th, 2008 Doctors at the Shore Medical Center in New Rochelle have something that millions of type 2 diabetes patients want to hear, a proposed treatment for the disease. Dr. Mahdu Rangraj and Dr.
New Painless & Fast Diabetes Test May Improve Diabetes Detection in Early StagesMay 16th, 2008 Scientists at the Med star Research Institute, Washington D.C. claimed to have invented a new way to replace the traditional diabetes testing method.
Common blood test may help predict diabetes nerve lossMay 19th, 2009 WASHINGTON - A common blood test for triglycerides can help doctors identify which diabetes patients are more vulnerable to serious, common complication of neuropathy, say researchers. Neuropathy is a condition in which nerves are damaged or lost with resulting numbness, tingling and pain, often in the hands, arms, legs and feet.