Doctor Says Glimepiride & Metformin Combo Acts Synergestically in Type 2 Diabetes ( NIDDM ) Treatment醫生說，格列美脲與二甲雙胍組合的行為， synergestically在2型糖尿病（非胰島素依賴型糖尿病）的治療
Type 2 diabetes is an increasingly common chronic disease that occurs in people who have difficulty in either generating sufficient insulin or using it. 2型糖尿病是一種越來越常見慢性疾病，發生在人誰遇到困難，要么產生足夠的胰島素或使用它。 Technically speaking, Type 2 diabetes is a progressive disorder with a consistent and steady increase in glycosylated hemoglobin (HbA1c) over time associated with enhanced risk of micro- and macrovascular complications (read eye and kidney diseases among host of others) and a substantial reduction in life expectancy.技術上來說， 2型糖尿病是一個漸進的障礙與一致的和穩步增加，糖化血紅蛋白（糖化血紅蛋白）隨著時間的推移與加強風險微型和大的並發症（閱讀眼睛和腎臟疾病之間的東道國等）並大幅削減預期壽命。
Glimepiride is a white to yellowish-white, crystalline, odorless to practically odorless powder formulated into tablets of 1-mg, 2-mg, and 4-mg strengths for oral administration. 格列美脲是一種白色至黃白色，結晶，無臭無味，切實制定成粉末粒1毫克， 2毫克和4毫克的優勢，為口服給藥。
Glimepiride works by increasing the amount of insulin that the pancreas releases while also encouraging the use of sugar in the blood by the cells in the body which need it.格列美脲工程，增加的數額即胰島素的胰腺新聞稿，同時也鼓勵使用糖在血液中由細胞在體內的需要。
Glimepiride is indicated as an adjunct to diet and exercise to lower the blood glucose in patients with noninsulin-dependent (Type 2) diabetes mellitus (NIDDM) whose hyperglycemia cannot be controlled by diet and exercise alone.格列美脲是表示，作為輔助飲食和運動，以降低血糖水平的患者noninsulin依賴性（ 2型）糖尿病（非胰島素依賴型糖尿病）的高血糖無法控制飲食和運動。 Glimepiride may be used concomitantly with metformin when diet, exercise, and glimepiride or metformin alone do not result in adequate glycemic control.格列美脲可用於與此同時二甲雙胍時，飲食，運動，和格列美脲或二甲雙胍單不結果，在適當的血糖控制。
Metformin , on the other hand, reduces the amount of glucose released from the liver and increases the amount taken up and used by the rest of the body. 二甲雙胍 ，另一方面，減少的數額葡萄糖釋放出來的肝臟和增加的數額所採取的行動和所用的，其餘的屍體。 The drug also reduces the level of fats in blood and helps people stabilize or reduce their weight, which incidentally has a distinct potential for abuse.毒品也減少了水平，脂肪在血液和幫助人們穩定或減少它們的重量，順便具有明顯的濫用的可能性。
“Many people with Type 2 diabetes will require combination treatment to achieve a much-improved glycemic control and oral hypoglycemic agent Solosamet tablet (combination of 2 mg glimepiride and 500 mg of metformin) holds so much promise for individuals with Type 2 diabetes,” said Dr. Araceli Panelo, a diabetologist and executive director of the Institute for the Studies of Diabetes Foundation. “很多人與2型糖尿病患者將需要綜合治療，以達致大大改善血糖控制及口服降糖劑solosamet片（組合2毫克格列美脲和500毫克二甲雙胍）持有這麼多的承諾，為個人與2型糖尿病，說： ”博士araceli panelo ， diabetologist和研究所執行主任為研究糖尿病的基礎。
Dr. Panelo explained that Type 2 is a complex disease and one could get significantly better therapeutic effects by targeting different systems: a glimepiride to help the pancreas while metformin to work on the liver. panelo博士解釋說， 2型是一個複雜的疾病和可以得到顯著更好的治療效果，針對不同的制度：一格列美脲，以幫助胰腺，而二甲雙胍工作，對肝臟。 Source: Inquirer資料來源：詢問者
“Combining drugs can give patients lower doses, fewer side effects, and better glycemic control,” the doctor concluded. “相結合的藥物可讓病人劑量較低，較少副作用，更好地控制血糖， ”醫生的結論。
Note that some people have developed a life-threatening condition called lactic acidosis while taking metformin .請注意，有些人已制定了一項危及生命的條件，所謂的乳酸酸中毒 ，同時考慮二甲雙胍 。 Get emergency medical help if you have any of these symptoms of lactic acidosis: weakness, increasing sleepiness, slow heart rate, cold feeling, muscle pain, shortness of breath, stomach pain, feeling light-headed, and fainting.獲得緊急醫療幫助，如果您有任何這些症狀乳酸酸中毒：軟弱，增加嗜睡，心率緩慢，冷的感覺，肌肉痛，呼吸急促，胃痛，感覺輕的頭腦，和昏厥。
Personally I would like to see some hard numbers (read: double-blind-placebo-controlled clinical trials) and possibly a study on long term complications before jumping to conclusions.我個人希望看到一些努力號碼（閱讀：雙盲-安慰劑對照臨床試驗）和可能的研究長期並發症的前跳到結論。
Filed under提起下 Diabetes糖尿病 , ， Glimepiride格列美脲 , ， Metformin二甲雙胍 , ， NIDDM非胰島素依賴型糖尿病 | |
