Thiazolidinediones, a widely used class of diabetes drugs can lead to bone fracture risk. Recent study in Switzerland proves that Pioglitazone and rosiglitazone, widely used drugs of the class, can lead to problems like slower bone formation and faster bone loss. It can be mentioned that both of two drugs account for 21 percent of oral diabetes medications prescribed in the United States and 5 percent of those in Europe respectively.
Come spring and the American Chemical Society is ready to reveal identity of their experimental drugs which is ready to be tested on human being. This year the annual event took place at the Morial Convention Center in New Orleans. To start with, the new medicine called Cevoglitazar is claimed to be effective on diabetes in a manner which is different from the others, said sources. Besides diabetes, the medicine is effective on obesity too. The manufacturer of the medicine, Novartis is said to be relied heavily on the computer models for proper design. Instead of halting the actions of enzymes, the medicine, is designed to be effected on the proteins called PPAR alpha and gamma.
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Researchers at Kaiser Permanente’s Department of Research and Evaluation, find that women who developed diabetes before pregnancy, may have problems with their blood-sugar control throughout the pregnancy. The organs of a baby is developed at the early stage of pregnancy, women need to reduce their risks before getting pregnant.
Murat Akyol, a pioneering Edinburgh based surgeon is planning to carry out life-saving operations on diabetics in the Capital. The operation, if successful will be able to vastly improve their quality of life and in some cases actually saving it.
Kaiser Permanente Medical Group, in Oakland, California, reported that women who gained about 5 to 22 pounds per year during the 5 years prior to pregnancy were 2.5 times more likely to develop gestational diabetes. Thus the study finds that would-be pregnant women decrease their likelihood of developing gestational diabetes by not gaining weight, study findings suggest.
A report published at the The journal Ophthalmology, shows that Primary open-angle glaucoma, most common form of glaucoma, is more likely to be developed among the diabetic women. The study supports the notion that type 2 diabetes is associated with an increased risk of glaucoma. The study was conducted by researchers at the Massachusetts Eye and Ear Infirmary.
A study published in the journal Diabetes Care states that people having the combination of type 2 diabetes and minor depression have a 67% greater risk of dying, while people with both diabetes and major depression have a 130% greater chance of dying, compared to those who have type 2 diabetes alone.
The researchers at the Salk Institute for Biological Studies have claimed to identify the probable molecular basis for the the diabetes — Alzheimer’s interaction. The risk of Alzheimer’s in the diabetics are usually higher. The probable interaction between the two remained unexplained for a long time. The study led by David R. Schubert, professor in the Cellular Neurobiology Laboratory, seems to solve the problem.
As part of chronic pancreatitis treatment, the doctors at the University of Cincinnati’s Pancreatic Disease Center has offfered the surgical solution to remove the pancreas to harvest islet cells from the organ, and then re-implanted the cells into his body to help manufacture insulin. The hospital has completed around 100 such treatment successfully, as the process has cured many from debilitating pain, said surgeon Syed Ahmad.
Vildagliptin, a new treatment for type 2 diabetes is reported to be more effective in blood sugar control. It does not cause weight gain and is associated with a low incidence of hypoglycaemia. Vildagliptin is available both alone and in a combination tablet with metformin and offers physicians prescribing flexibility and convenience for patients. Vildagliptin, an oral treatment for type2 diabetes, demonstrated additional reductions in HbA1c of 1.1% versus placebo when added to metformin(1).
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